Antigen Cross-Presentation of Immune Complexes
نویسندگان
چکیده
منابع مشابه
Antigen Cross-Presentation of Immune Complexes
The ability of dendritic cells (DCs) to cross-present tumor antigens has long been a focus of interest to physicians, as well as basic scientists, that aim to establish efficient cell-based cancer immune therapy. A prerequisite for exploiting this pathway for therapeutic purposes is a better understanding of the mechanisms that underlie the induction of tumor-specific cytotoxic T-lymphocyte (CT...
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Matthew D. Griffin1, Nianzeng Xing1,3, and Rajiv Kumar1,2 1Department of Internal Medicine, Division of Nephrology, and 2Department of Biochemistry and Molecular Biology and Mayo Proteomics Research Center, Mayo Clinic and Foundation, Rochester, Minnesota 55905; email: [email protected]; [email protected]; [email protected] 3Current address: Department of Urology, Beijing Chao Yang Ho...
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چکیده ندارد.
15 صفحه اولAutophagy-assisted antigen cross-presentation
It is generally believed that most tumor antigens are passively released from either health or dying tumor cells as intact soluble antigens, peptide fragments complexed with heat shock proteins (HSPs), or packaged in secretary vesicles in the form of microparticles or exosomes. The passive release of tumor antigens is generally non-inflammatory and non-immunogenic; however, results from others ...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2014
ISSN: 1664-3224
DOI: 10.3389/fimmu.2014.00140